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HKU launches clinical trial in Hong Kong to treat chronic hepatitis B patients

Existing medication only suppresses virus and has to be taken for decades, researcher says

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HKU’s Li Ka Shing Faculty of Medicine. Photo: SCMP

The University of Hong Kong (HKU) has launched a clinical trial for a gene-related therapy aimed at treating chronic hepatitis B infection, giving patients hope for a cure in the future.

Professor Yuen Man-fung, chief of the division of gastroenterology and hepatology at HKU’s medical faculty, said on Thursday that existing medication for hepatitis B patients could only suppress the virus and had to be taken for decades.

He expected that the new treatment could enable patients to discontinue long-term medication.

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“If we can suppress the virus and also eradicate the virus if possible, then the patients will not suffer or will have a minimal risk or lower risk of suffering from liver cancer development and cirrhosis or liver failure,” he said.

“And that obviously will bring hope … [to the] patients.”

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Chronic hepatitis B affects more than 300 million people worldwide and is a primary cause of liver cirrhosis, cancer and liver failure. Around 6.2 per cent of the population of Hong Kong is affected by the condition.

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